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Original Article
- Changes in seroprevalence of hepatitis B surface antigen and epidemiologic characteristics in the Republic of Korea, 1998-2013
- Hyerin Lee, Hyungmin Lee, Yumi Cho, Kyungwon Oh, Moran Ki
- Epidemiol Health. 2015;37:e2015055. Published online December 23, 2015
- DOI: https://doi.org/10.4178/epih/e2015055
- 14,577 View
- 252 Download
- 13 Web of Science
- 9 Crossref
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Abstract
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AbstractOBJECTIVES
This study investigated changes in hepatitis B seroprevalence from 1998 to 2013, and to identify differences in epidemiologic characteristics between hepatitis B surface antigen (HBsAg)-positive and HBsAg-negative people.METHODSHBsAg seropositive rates were compared by year, sex, and age using the blood test data from the periods I to VI (1998-2013) of the Korea National Health and Nutrition Examination Survey. Interviews and self-administered surveys were conducted to collect data on health behavior, quality of life, comorbidities, and health care utilization.RESULTSHBsAg seropositive rates in the Republic of Korea decreased from 4.6% in 1998 to 2.9% in 2008, and then remained the same for the next five years. While seropositive rates by age were the highest at 35 to 39 years of age in 1998, it peaked at 50 to 54 years of age in 2013. HBsAg-positive people showed high values from two liver function tests, including glutamic-oxaloacetic transaminase and glutamic-pyruvic transaminase, and the prevalence rates of liver cirrhosis and liver cancer were also significantly high. Indices for health behavior and quality of life showed no significant differences between HBsAg-positive and HBsAg-negative people.CONCLUSIONSWhile HBsAg seropositive rates tended to decline after 1998, there have been no significant changes over the most recent five years. We should focus on treatment of existing hepatitis B patients along with immunization programmes to prevent new hepatitis B infections. In addition, it may be necessary to encourage HBsAg-positive people to follow healthier life-styles in order to prevent further progression of hepatitis B to liver cirrhosis and liver cancer. -
SummaryKorean summary
한국 국민건강영양조사 자료로 본 HBsAg 양성률은 1998 년 4.6%에서 2008 년에 2.9%로 감소한 이후 5 년간 증감없이 2013 년에 2.9%로 나타났다. 한국 HBsAg 양성률을 더욱 감소시키기 위해서는 예방접종사업뿐 아니라 B형 간염 환자 치료를 보다 적극적으로 해야 될 것으로 보인다. 또한 HBsAg 양성자는 간경화나 간암 예방을 위해 건강한 생활습관을 가지도록 노력하는 것이 필요하다. -
Citations
Citations to this article as recorded by
- Shifting Epidemiology of Hepatocellular Carcinoma in Far Eastern and Southeast Asian Patients: Explanations and Implications
Nguyen H. Tran
Current Oncology Reports.2022; 24(2): 187. CrossRef - Proportion of People Who Are Positive for HBsAg and Anti-HCV Antibody Among Participants in a Community Screening Campaign in Malaysia
Zhuo-Zhi Lim, Jau Shya Teo, Ah Choon Tan, Teck-Onn Lim
Hepatitis Monthly.2022;[Epub] CrossRef - The changing epidemiology of liver diseases in the Asia–Pacific region
Martin C. S. Wong, Jason L. W. Huang, Jacob George, Junjie Huang, Colette Leung, Mohammed Eslam, Henry L. Y. Chan, Siew C. Ng
Nature Reviews Gastroenterology & Hepatology.2019; 16(1): 57. CrossRef - Incidence and Overall Survival of Biliary Tract Cancers in South Korea from 2006 to 2015: Using the National Health Information Database
Byung-Woo Kim, Chang-Mo Oh, Hwa Young Choi, Joong-Won Park, Hyunsoon Cho, Moran Ki
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Journal of the American College of Cardiology.2019; 73(25): 3295. CrossRef - Negative Association of Hepatitis B Virus With Hearing Impairment
SKM Azizul Islam, Jin Wook Chung, Young-Sil Lee, HoChan Cho, Seong-Su Moon
American Journal of Audiology.2018; 27(3): 324. CrossRef - Response to hepatitis B vaccination in patients with inflammatory bowel disease: a prospective observational study in Korea
Ji Young Chang, Sung-Ae Jung, Chang Mo Moon, Seong-Eun Kim, Hye-Kyung Jung, Ki-Nam Shim
Intestinal Research.2018; 16(4): 599. CrossRef - Recognition criteria for occupational cancers in relation to hepatitis B virus and hepatitis C virus in Korea
Hogil Kim, Yun Kyung Chung, Inah Kim
Annals of Occupational and Environmental Medicine.2018;[Epub] CrossRef - Identification of Novel A2/C2 Inter-Genotype Recombinants of Hepatitis B Virus from a Korean Chronic Patient Co-Infected with Both Genotype A2 and C2
So-Young Lee, Seung-Hee Lee, Ji-Eun Kim, Hong Kim, Kijeong Kim, Yoon-Hoh Kook, Bum-Joon Kim
International Journal of Molecular Sciences.2017; 18(4): 737. CrossRef
- Shifting Epidemiology of Hepatocellular Carcinoma in Far Eastern and Southeast Asian Patients: Explanations and Implications
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